{"id":11961,"date":"2010-04-05T07:00:22","date_gmt":"2010-04-05T11:00:22","guid":{"rendered":"https:\/\/today.uconn.edu\/?p=11961"},"modified":"2011-05-31T12:40:07","modified_gmt":"2011-05-31T16:40:07","slug":"new-research-building-slated-to-open-in-farmington","status":"publish","type":"post","link":"https:\/\/today.uconn.edu\/2010\/04\/new-research-building-slated-to-open-in-farmington\/","title":{"rendered":"New Research Building Slated to Open in Farmington"},"content":{"rendered":"<figure id=\"attachment_11903\" aria-describedby=\"caption-attachment-11903\" style=\"width: 344px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2010\/03\/FarmintonAve3_lg.jpg\"><img decoding=\"async\" class=\"size-medium wp-image-11903 img-responsive lazyload\" title=\"An architect's rendering of 400 Farmington Avenue.\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2010\/03\/FarmintonAve3_lg-300x225.jpg\" alt=\"&lt;p&gt;An architect's rendering of 400 Farmington Avenue. Supplied by the UConn Health Center&lt;\/p&gt;\" width=\"344\" height=\"257\" data-srcset=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2010\/03\/FarmintonAve3_lg-300x225.jpg 300w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2010\/03\/FarmintonAve3_lg.jpg 700w\" data-sizes=\"(max-width: 344px) 100vw, 344px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 344px; --smush-placeholder-aspect-ratio: 344\/257;\" \/><\/a><figcaption id=\"caption-attachment-11903\" class=\"wp-caption-text\">An architect&#39;s rendering of 400 Farmington Avenue. Supplied by the UConn Health Center<\/figcaption><\/figure>\n<p>The University of Connecticut is just months away from opening a new research building in Farmington to enhance Connecticut\u2019s role as a leader in innovative high tech research and technology transfer in the areas of stem cell biology, advanced microscopy and imaging, computational biology and genetics.<\/p>\n<p>Especially designed with open labs that flow into each other and office areas located on hallways running between labs, the new Cell and Genomic Sciences Building intends to promote interdisciplinary research among the academic and industry chemists, geneticists, physicists, mathematicians, cell biologists, and computer scientists housed there. This collaborative effort aims to capitalize on the power of different areas of scientific expertise to revolutionize the practice of medicine.<\/p>\n<p>\u201cOur goal is to maximize the state\u2019s investment in stem cell research by establishing an infrastructure to support scientists in their quest of turning discoveries at the bench into therapies for diseases such as autism and cancer and to advance the field of regenerative medicine,\u201d says Dr. Marc Lalande, senior associate dean for research planning and coordination at the UConn Health Center and director of UConn\u2019s Stem Cell Institute, as well as professor and chairman of the medical school\u2019s genetics and developmental biology department. \u201cThis is an unprecedented opportunity for us.\u201d<\/p>\n<p>Purchased by UConn with Board of Trustees\u2019 approval in 2007, a former research and testing facility at 400 Farmington Avenue \u2013 across the street from UConn\u2019s Health Center campus \u2013 has been undergoing a $52 million transformation and is to be equipped with the latest technologies for studying cells and their genomes. The new 117,000 square foot building is expected to open in July 2010.<\/p>\n<p>The renovated building will house research laboratories, offices, a 100-seat auditorium, cafeteria, and incubator space for businesses eager to commercialize stem cell science. Designed by the Boston laboratory architecture firm Goody Clancy, the renovations will meet the requirements of a LEED Silver rating, according to project manager Kevin Norton.<\/p>\n<p>The LEED (Leadership in Energy and Environmental Design) green building rating system \u2013 developed and administered by the U.S. Green Building Council \u2013 is the industry standard for measuring building sustainability.<\/p>\n<p>Currently more than 100 construction workers are busy completing the mechanical and electrical systems, installing finishes, laboratory casework, interior window assemblies, and skylights over the corridors of the one-story structure.<\/p>\n<h3>Opportunities for Collaboration<\/h3>\n<figure id=\"attachment_11902\" aria-describedby=\"caption-attachment-11902\" style=\"width: 327px\" class=\"wp-caption alignright\"><a href=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2010\/03\/FarmingtonAve0009_lg.jpg\"><img decoding=\"async\" class=\"size-medium wp-image-11902 img-responsive lazyload\" title=\"An open lab area with wood plank ceilings in the Cell and Genome Sciences Building.\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2010\/03\/FarmingtonAve0009_lg-300x168.jpg\" alt=\"&lt;p&gt;An open lab area with wood plank ceilings in the Cell and Genome Sciences Building. Photo by Kevin Norton&lt;\/p&gt;\" width=\"327\" height=\"182\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 327px; --smush-placeholder-aspect-ratio: 327\/182;\" \/><\/a><figcaption id=\"caption-attachment-11902\" class=\"wp-caption-text\">An open lab area with wood plank ceilings in the Cell and Genome Sciences Building. Photo by Kevin Norton<\/figcaption><\/figure>\n<p>\u201cThe overriding intent is to provide sufficient internal transparency to allow the entire research community in the building to interact, while providing natural light to internal spaces,\u201d says Norton.<\/p>\n<p>Scientists in the building will be involved in a wide spectrum of research projects, including the design and construction of new laser-based microscopes, computer simulation of living processes inside cells, and sequencing of human and animal genomes, says Lalande. Being located close to UConn\u2019s Health Center will support the goal of translating basic research findings to clinical trials, he adds.<\/p>\n<p>Two corridors lead off the entrance lobby of the building to private areas dispersed around the facility for focused research.<\/p>\n<p>Three major research programs will be re-located from the Health Center to the new facility: the UConn Stem Cell Institute (UCSCI), the R.D. Berlin Center for Cell Analysis and Modeling (CCAM), and the Department of Genetics and Developmental Biology. Together these three programs include about 180 scientists and their staff.<\/p>\n<ul>\n<li>The UCSCI was established after the state, in 2005, enacted legislation to fund stem cell research through the Connecticut State Stem Cell Advisory Committee. Over the first three rounds of competition for the state funds, UConn researchers won $20.8 million \u2013 the majority of awards granted. The funding supports more than 32 laboratories at both the Farmington and Storrs campuses. UConn scientists have submitted 44 applications for the state\u2019s fourth grant competition round, which begins next month.<\/li>\n<p>UConn has spent more than $1 million to equip the human embryonic stem cell core facility that trains researchers and lab workers from around the state on lab techniques for stem cell research; 114 have been trained to date.<\/p>\n<p>Recently, staff of the core facility developed induced pluripotent human stem cells, or iPS cells, which behave like embryonic stem cells and increasingly are being used by researchers to generate <em>in vitro<\/em> models of human disease.<\/p>\n<p>The on-site presence of the UCSCI and the stem cell core facility will provide both hands-on expertise and resources to the wide range of investigators in the new building.<\/p>\n<li>CCAM\u2019s multidisciplinary team uses cutting-edge imaging, microscopy, and computational modeling to more accurately analyze living cells. CCAM has also developed a computer software and database system \u2013 the Virtual Cell \u2013 that allows researchers to construct computational models of cells, perform simulations, and analyze the results of those simulations to better understand cell physiology. More than 2,000 scientists from around the world have used the Virtual Cell to carry out simulations.<\/li>\n<p>To handle these simulations (some are quite large), the new Center will house CCAM\u2019s High Performance Computing Facility, which also provides computer support to the CCAM microscopy facility and other research projects of individual UConn faculty members.<\/p>\n<li>Equipped with $1.1 million of state-of-the-art technology to read entire genomes, the translational genomics core facility will have all the equipment necessary for DNA analysis and sequencing, gene expression analysis, genotyping, and the associated bioinformatics infrastructure to facilitate data analysis.<\/li>\n<p>The new building will afford the 17 scientists from the Department of Genetics and Developmental Biology moving there the opportunity to work with their colleagues in ways that haven\u2019t been possible before, and to use these new tools to isolate and study rare cells.<\/ul>\n<p>Having these programs in the same building along with researchers applying a broad range of cutting-edge approaches will significantly speed up cell research at UConn, Lalande says.<\/p>\n<p>The potential of the new facility and continued stem cell funding by the state has already helped recruit two new faculty with expertise in stem cell biology and nanomedicine who are expected to join the new building\u2019s research community later this summer, he adds.<\/p>\n<p>\u201cWe\u2019re thinking about the intersection of cell biology, genetics, and computer science, and other disciplines that inform those areas,\u201d he says.<\/p>\n<p>Researchers will also find it easier to communicate with each other about their work, Lalande says, fostering collaborations that could lead to new insights into cell biology: \u201cThis building is designed to drive cross-pollination of scientific ideas to a new level.\u201d<\/p>\n<h3>From Lab to Marketplace<\/h3>\n<figure id=\"attachment_11901\" aria-describedby=\"caption-attachment-11901\" style=\"width: 327px\" class=\"wp-caption alignright\"><a href=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2010\/03\/FarmingtonAve0003_lg.jpg\"><img decoding=\"async\" class=\"size-medium wp-image-11901 img-responsive lazyload\" title=\"A lab area being constructed in the Cell and Genome Sciences Building.\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2010\/03\/FarmingtonAve0003_lg-300x168.jpg\" alt=\"&lt;p&gt;A lab area being constructed in the Cell and Genome Sciences Building. Photo by Kevin Norton&lt;\/p&gt;\" width=\"327\" height=\"181\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 327px; --smush-placeholder-aspect-ratio: 327\/181;\" \/><\/a><figcaption id=\"caption-attachment-11901\" class=\"wp-caption-text\">A lab area being constructed in the Cell and Genome Sciences Building. Photo by Kevin Norton<\/figcaption><\/figure>\n<p>The new building\u00a0 will also expand the work of UConn\u2019s Office of Technology Commercialization, including the Technology Incubation Program \u2013 UConn\u2019s \u00a0business incubator \u2013 by providing offices, conference rooms, and laboratories for six start-up biotechnology companies.<\/p>\n<p>\u201cWhile our scientists may generate the next stem cell breakthrough, to bring them to market there must be a group of people with the skills not only to start a company, but to help it grow,\u201d says Rita Zangari, interim director of the Office of Technology Commercialization and executive director of the Technology Incubation Program.<em> <\/em><\/p>\n<p>The new building has already helped to attract two bioscience companies, Zangari says. One company seeks to use stem cells in bone cement products, while the other \u2013 relocating to Connecticut from Massachusetts \u2013 is conducting research using stem cells extracted from tooth pulp for therapeutic use in combating degenerative diseases.<\/p>\n<p>\u201cHaving the resources in place for our researchers and their industry partners to move discoveries from the lab to the marketplace fosters a climate in which ideas are easily exchanged and partnerships are developed,\u201d Zangari says. \u201cCollaboration is the essence of UConn\u2019s power to generate new discoveries and then build companies and jobs around them.\u201d<\/p>\n<p><input id=\"gwProxy\" type=\"hidden\" \/> <input id=\"jsProxy\" onclick=\"jsCall();\" type=\"hidden\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The goal of the new facility is to establish an infrastructure that will support scientists in their quest to turn discoveries at the bench into therapies for disease.<\/p>\n<p><input id=\"gwProxy\" type=\"hidden\" \/> <input id=\"jsProxy\" onclick=\"jsCall();\" type=\"hidden\" \/><\/p>\n","protected":false},"author":15,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_crdt_document":"","wds_primary_category":0,"wds_primary_series":0,"wds_primary_attribution":0,"footnotes":""},"categories":[1],"tags":[],"magazine-issues":[],"coauthors":[46],"class_list":["post-11961","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"pp_statuses_selecting_workflow":false,"pp_workflow_action":"current","pp_status_selection":"publish","acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-14 02:25:48","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/11961","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/comments?post=11961"}],"version-history":[{"count":6,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/11961\/revisions"}],"predecessor-version":[{"id":37125,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/11961\/revisions\/37125"}],"wp:attachment":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media?parent=11961"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/categories?post=11961"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/tags?post=11961"},{"taxonomy":"magazine-issue","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/magazine-issues?post=11961"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/coauthors?post=11961"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}