{"id":136888,"date":"2018-04-23T15:51:35","date_gmt":"2018-04-23T19:51:35","guid":{"rendered":"https:\/\/today.uconn.edu\/?p=136888"},"modified":"2018-04-23T16:45:56","modified_gmt":"2018-04-23T20:45:56","slug":"first-potential-biomarker-noise-induced-hearing-loss-identified","status":"publish","type":"post","link":"https:\/\/today.uconn.edu\/2018\/04\/first-potential-biomarker-noise-induced-hearing-loss-identified\/","title":{"rendered":"First Potential Biomarker for Noise-Induced Hearing Loss Identified"},"content":{"rendered":"

A new study presented\u00a0at the 53rd\u00a0American Neurotology Society<\/a>\u00a0Annual Spring Meeting\u00a0reveals the first potential biomarker for noise-induced hearing loss. The findings of the collaborative research study were jointly presented by Sensorion<\/a> and UConn Health<\/a>.<\/p>\n

The laboratory study identified changes in prestin blood levels, an outer hair cell protein, in a preclinical model with noise-induced hearing loss. Researchers analyzed the blood samples for the amount of circulating blood serum prestin levels. The study showed that the severity of hearing loss correlated with amount of change in levels of prestin circulating in the blood.<\/p>\n

\u201cNoise-induced hearing loss is a devastating condition that significantly affects patients\u2019 quality of life,\u201d\u00a0said Dr.\u00a0Kourosh Parham, associate professor and director of research in UConn Health\u2019s Division of Otolaryngology<\/a>, Head & Neck Surgery.\u00a0\u201cWorking with Sensorion to arrive at these results has been an opportunity to introduce the field of otology to a new potential biomarker candidate for the future possible early diagnosis of hearing loss in patients before their condition becomes severe.\u201d<\/p>\n

\u201cThe collaboration of Sensorion with UConn Health\u2019s Division of Otolaryngology has resulted in the discovery of a potentially vital biomarker for the early diagnosis of hearing loss,\u201d said\u00a0Nawal Ouzren, chief executive officer of Sensorion.\u00a0\u201cAs with many diseases, the earlier clinicians can diagnose a disease, the better our chances for effective intervention. Sensorion intends to integrate measuring prestin in the clinical trial of its lead compound SENS-401.\u201d<\/p>\n

The oral presentation, “Noise-Induced Trauma Produces a Temporal Pattern of Change in Serum Levels of the Outer Hair Cell Biomarker Prestin,\u201d <\/em>was presented at the American Neurotology Society Annual Spring Meeting, one of the featured meetings of the Combined Otolaryngology Spring Meetings (COSM), held in National Harbor, Maryland from April 20 to 22. The mission of this major annual scientific event is to bring together ear, nose, and throat societies for the purpose of spreading and exchanging the latest clinical and basic scientific research.<\/p>\n

To learn more about UConn Health\u2019s Dr. Kourosh Parham, visit\u00a0<\/em>here<\/em><\/a>\u00a0or the\u00a0<\/em>website<\/em><\/a>\u00a0of the Division of Otolaryngology. To read more about Parham’s research, click here<\/a>.<\/em><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

UConn Health physician-researcher Kourosh Parham says the new biomarker may facilitate early diagnosis of hearing loss in patients before their condition becomes severe.<\/p>\n","protected":false},"author":98,"featured_media":115535,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_crdt_document":"","wds_primary_category":0,"wds_primary_series":0,"wds_primary_attribution":0,"footnotes":""},"categories":[2231,2076,179],"tags":[],"magazine-issues":[],"coauthors":[1873],"class_list":["post-136888","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-well-being","category-research","category-uconn-health"],"pp_statuses_selecting_workflow":false,"pp_workflow_action":"current","pp_status_selection":"publish","acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-24 13:05:23","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/136888","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/users\/98"}],"replies":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/comments?post=136888"}],"version-history":[{"count":6,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/136888\/revisions"}],"predecessor-version":[{"id":136918,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/136888\/revisions\/136918"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media\/115535"}],"wp:attachment":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media?parent=136888"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/categories?post=136888"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/tags?post=136888"},{"taxonomy":"magazine-issue","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/magazine-issues?post=136888"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/coauthors?post=136888"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}