{"id":152648,"date":"2019-08-02T10:08:25","date_gmt":"2019-08-02T14:08:25","guid":{"rendered":"https:\/\/today.uconn.edu\/?post_type=school-college-post&#038;p=152648"},"modified":"2019-08-06T11:54:25","modified_gmt":"2019-08-06T15:54:25","slug":"new-cancer-clinical-practice-guideline-severe-jaw-condition-stresses-collaboration-dentists-oncologists","status":"publish","type":"post","link":"https:\/\/today.uconn.edu\/2019\/08\/new-cancer-clinical-practice-guideline-severe-jaw-condition-stresses-collaboration-dentists-oncologists\/","title":{"rendered":"New Cancer Clinical Practice Guideline for Severe Jaw Condition Stresses  Collaboration Between Dentists and Oncologists"},"content":{"rendered":"<p>A new clinical practice guideline that stresses the importance of collaboration between dentists and medical oncologists to prevent, diagnose, and treat medication-related osteonecrosis of the jaw (MRONJ) in cancer patients was recently published by a team of experts, including leadership from UConn School of Dental Medicine faculty Dr. Douglas Peterson.<\/p>\n<p>MRONJ is a severe side effect in patients using drugs to minimize risk for skeletal bone fractures during cancer treatment. These drugs can cause lesions to form in the jaw bone, with failure to heal over a several week timeframe.\u00a0 The bone lesions can cause significant morbidity for the cancer patient, including pain, decreased quality of life, and need for extensive jaw surgery.<\/p>\n<p>The document, published on July 22, 2019 in the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31329513\">Journal of Clinical Oncology<\/a>, is a first-in-kind joint MRONJ guideline that has been developed by members of the Multinational Association of Supportive Care in Cancer \/ International Society of Oral Oncology (MASCC\/ISOO) and the American Society of Clinical Oncology (ASCO).\u00a0 These two organizations are highly impactful in oncology at the international level.<\/p>\n<p>According to the guideline, an ongoing collaboration between the dentist and the oncologist is essential to optimal cancer patient care when it comes to preventing, diagnosing, and treating MRONJ.<\/p>\n<p>Peterson, professor of oral medicine, was recently named chair-elect of ASCO\u2019s Clinical Practice Guidelines Committee, the parent committee that oversees all ASCO guidelines.\u00a0 Approximately 45,000 oncology professionals are members of ASCO, and represent all oncology subspecialties.\u00a0 International members comprise approximately one-third of ASCO\u2019s membership, and come from more than 150 countries.\u00a0 After serving one year as chair-elect, Peterson will become chair of ASCO\u2019s guidelines committee.<\/p>\n<p>\u201cThe collaboration between MASCC\/ISOO and ASCO to produce this guideline represents the first time\u00a0these two\u00a0internationally prominent oncology organizations have partnered to develop this type of information,\u201d said Peterson. \u201cI am delighted to see\u00a0publication of this guideline come to fruition, and am looking forward to continued development of the next joint oncology guideline that is currently in production.&#8221;<\/p>\n<p>To create this guideline, MASCC\/ISOO and ASCO convened a multidisciplinary expert panel to evaluate the evidence\u2014including a systematic review of the current literature\u2014and formulate recommendations.<\/p>\n<p>The clinical recommendations in the guideline also include ensuring that MRONJ is diagnosed by a clinician with experience in the management of MRONJ, and taking conservative measures for treating MRONJ whenever possible.<\/p>\n<p>In developing the guideline, Peterson was joined by a team of dental and medical experts from:<\/p>\n<p>Sheba Medical Center, Israel<br \/>\nTel Aviv University, Israel<br \/>\nIcahn School of Medicine at Mt Sinai, New York, NY<br \/>\nUniversity of Michigan, Ann Arbor, MI<br \/>\nAmerican Society of Clinical Oncology, Alexandria, VA<br \/>\nHofstra North Shore-LIJ School of Medicine, Hempstead, NY<br \/>\nStony Brook School of Dental Medicine, Stony Brook, NY<br \/>\nNew York Center for Orthognathic and Maxillofacial Surgery, New York, NY<br \/>\nUniversity of Florida College of Dentistry, Gainesville, FL<br \/>\nMcMaster University, Canada<br \/>\nDalhousie University, Canada<br \/>\nQueen Elizabeth II Health Sciences Centre, Canada<br \/>\nBreast Cancer Coalition of Rochester, Rochester, NY<br \/>\nVanderbilt University, Nashville, TN<br \/>\nUniversity of North Carolina Cancer Care at Nash, Rocky Mount, NC<br \/>\nCase Western Reserve University, Cleveland, OH<br \/>\nStanford University Medical Center, Stanford, CA<br \/>\nAarhus University, Denmark<br \/>\nNorthern Ontario School of Medicine, Canada.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new clinical practice guideline that stresses the importance of collaboration between dentists and medical oncologists to prevent, diagnose, and treat medication-related osteonecrosis of the jaw in cancer patients was recently published by a team of experts, including leadership from UConn School of Dental Medicine faculty Dr. Douglas Peterson.<\/p>\n","protected":false},"author":136,"featured_media":152649,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_crdt_document":"","wds_primary_category":0,"wds_primary_series":0,"wds_primary_attribution":0,"footnotes":""},"categories":[2166,1868],"tags":[],"magazine-issues":[],"coauthors":[2177],"class_list":["post-152648","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sdm","category-meds"],"pp_statuses_selecting_workflow":false,"pp_workflow_action":"current","pp_status_selection":"publish","acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-10 06:21:18","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/152648","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/users\/136"}],"replies":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/comments?post=152648"}],"version-history":[{"count":0,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/152648\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media\/152649"}],"wp:attachment":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media?parent=152648"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/categories?post=152648"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/tags?post=152648"},{"taxonomy":"magazine-issue","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/magazine-issues?post=152648"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/coauthors?post=152648"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}