{"id":160049,"date":"2020-04-24T07:48:29","date_gmt":"2020-04-24T11:48:29","guid":{"rendered":"https:\/\/today.uconn.edu\/?p=160049"},"modified":"2020-04-24T14:04:36","modified_gmt":"2020-04-24T18:04:36","slug":"op-ed-no-cbd-not-miracle-molecule-can-cure-coronavirus","status":"publish","type":"post","link":"https:\/\/today.uconn.edu\/2020\/04\/op-ed-no-cbd-not-miracle-molecule-can-cure-coronavirus\/","title":{"rendered":"Op-Ed: No, CBD is Not a Miracle Molecule that Can Cure Coronavirus"},"content":{"rendered":"

The claims for CBD\u2019s alleged healing powers have been so exaggerated that it\u2019s no surprise that a CBD maker was recently warned by the New York attorney general for <\/span>claiming that the molecule can fight COVID-19<\/a>. There are no credible animal or human studies showing CBD has any effect on SARS-CoV-2 or the course of COVID-19 infection.<\/span><\/span><\/p>\n

As professor and chair<\/a> of the Department of Pharmacy Practice at the University of Connecticut, I\u2019ve investigated many claims of vitamin cures for various illnesses over the decades, including CBD. <\/span><\/span><\/p>\n

Antioxidant vitamin cocktails<\/a> were once believed the new stars of the nutrition world. The cocktails, with vitamin E, beta-carotene and vitamin C, supposedly reduced the risk of heart disease, stroke and cancer. That story \u2013 derived from single-cell and small-animal studies \u2013 was captivating. Imagine taking a vitamin pill to halt free radical damage or keep your arteries from hardening.<\/span><\/span><\/p>\n

Next up was <\/span>soy<\/a> and <\/span>resveratrol<\/a>, so-called superfoods that could lower rates of heart disease and cancer; then <\/span>coenzyme Q10<\/a>, touted to prevent statin-induced muscle damage. All fell from grace when definitive studies were conducted. <\/span><\/span><\/p>\n

But the CBD hype is in a class by itself, as the misinformation for this cannabis-derived molecule exploded after <\/span>one drug containing cannabidiol \u2013 or CBD<\/a> \u2013 received Food and Drug Administration approval in 2018 \u2013 for treatment of seizures associated with two rare forms of epilepsy. <\/span><\/span><\/p>\n

How strong is the CBD data?<\/span><\/span><\/b><\/p>\n

On behalf of the Journal of Clinical Pharmacology, I recently <\/span>conducted a review<\/a> that evaluated the evidence supporting the use of CBD.<\/span><\/span><\/p>\n

There is strong evidence that CBD may do some good for some people. CBD can prevent seizures in people with two rare diseases, <\/span>Lennox-Gestaut<\/a> and <\/span>Dravet syndrome<\/a>. CBD consistently shows benefits when used before an anxiety-provoking event, <\/span>like public speaking<\/a><\/span>\u200b<\/span> (although not as effective as clonazepam, an FDA-indicated drug for performance anxiety). <\/span><\/span><\/p>\n

Limited studies show promising initial findings for other conditions, although more research is needed. CBD might help with <\/span>inflammation<\/a> of the joints or skin, sleep disturbances, chronic anxiety, psychosis and behavioral issues associated with <\/span>Fragile X syndrome<\/a>. But natural alternatives already exist that offer much more evidence for some of these benefits: <\/span>Melatonin<\/a> helps with sleep, <\/span>kava<\/a> for chronic anxiety and the <\/span>curcumin extract of turmeric<\/a> for general inflammation or <\/span>fatty liver disease<\/a>. <\/span><\/span><\/p>\n

CBD has been shown ineffective for treating symptoms of Parkinson\u2019s and Crohn\u2019s disease. Data on treating pain and muscle spasms is poor. As for preventing cancer, rosacea or the dozens of other things it\u2019s supposed to fix, that\u2019s pure speculation. <\/span><\/span><\/p>\n

The risks of CBD<\/span><\/span><\/h2>\n

CBD is a drug. The FDA allows it to be sold as a cosmetic and prescription product, and you can also buy it without a prescription. But just because it\u2019s in lots of things (seltzer, cupcakes and beer, to name a few) does not mean it\u2019s risk-free. <\/span>In the largest evaluation<\/a>, high doses of CDB induced mild liver damage in 17% of the people taking it. Severe or irreversible damage would have occurred had researchers not stopped the subjects from taking more. If you\u2019re taking CBD at home, without medical supervision, you would not know about the liver damage until it was acute. <\/span><\/span><\/p>\n

There are drug interactions too. Add CBD to other drugs you\u2019re taking and it might produce unexpected side effects, or cause those drugs to be less efficient. I wouldn\u2019t take CBD without checking with my doctor or pharmacist to assure me there were no risky drug interactions.<\/span><\/span><\/p>\n

Because CBD is a seizure medication, the FDA is concerned it could <\/span>promote suicidal thoughts,<\/a> as some <\/span>other seizure medications<\/a> do. Although no data supports that concern, CBD hasn\u2019t been studied long-term. The most common side effects of CBD include sleepiness and diarrhea, which happens in one-third of users, and vomiting and fever, which happens in 15%. <\/span><\/span><\/p>\n

You take <\/span>additional risks<\/a> if the CBD product is not certified by an outside laboratory. Without that, bacterial, fungal or heavy metal contamination of the CBD becomes more likely \u2013 so does mixing of the CBD with synthetic drugs. Many independent evaluations already show many products do not contain the amount of CBD they claim; some provide much less. <\/span><\/span><\/p>\n

Conversely, a few of the products contain more than the legal limit for THC. This places you at risk of arrest for marijuana possession. There are also other unhappy scenarios: You might have used a subpotent product and took 500 mg to get the desired benefits. Then after switching to a better-quality product, you take the same 500 mg and accidentally overdose. <\/span><\/span><\/p>\n

CBD is neither a miracle or snake oil. So far, the evidence \u2013 or lack of it, for most ailments \u2013 suggests the risks may outweigh the benefits.<\/span><\/span><\/p>\n

Eating a balanced diet, exercising regularly, getting enough sleep, maintaining a healthy body weight and managing stress are the basis of good health. Nowhere in there is a recommendation to adopt every health fad that comes along. But people are <\/span>psychologically attracted<\/a> to health fads because they are novel, they sound plausible (at least on the surface) and they\u2019re easy to use. What\u2019s more, there\u2019s the bandwagon effect: Nobody wants to be left out.<\/span><\/span><\/p>\n

But it\u2019s a mistake to believe that studies of <\/span>cells in a lab<\/a> are directly applicable to humans. It\u2019s a mistake to believe <\/span>testimonials from customers<\/a> in television commercials. For that matter, it\u2019s a mistake to believe much of the content in these advertisements. Some make <\/span>false claims<\/a>, some are selective in the information they provide and some suppress negative information about the product.<\/span><\/span><\/p>\n

\u00a0<\/span><\/span><\/p>\n

Originally published in The Conversation.<\/a>\u00a0<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Claims for CBD’s effectiveness in treating coronavirus are baseless hype rather than evidence-based evaluations, says UConn’s C. Michael White.<\/p>\n","protected":false},"author":68,"featured_media":160050,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_crdt_document":"","wds_primary_category":0,"wds_primary_series":0,"wds_primary_attribution":0,"footnotes":""},"categories":[2213,2231,1864,2225],"tags":[],"magazine-issues":[],"coauthors":[1902],"class_list":["post-160049","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-coronavirus","category-health-well-being","category-pharm","category-uconn-storrs"],"pp_statuses_selecting_workflow":false,"pp_workflow_action":"current","pp_status_selection":"publish","acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-27 11:16:41","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/160049","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/users\/68"}],"replies":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/comments?post=160049"}],"version-history":[{"count":2,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/160049\/revisions"}],"predecessor-version":[{"id":160262,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/160049\/revisions\/160262"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media\/160050"}],"wp:attachment":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media?parent=160049"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/categories?post=160049"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/tags?post=160049"},{"taxonomy":"magazine-issue","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/magazine-issues?post=160049"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/coauthors?post=160049"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}