{"id":203443,"date":"2008-08-19T19:31:50","date_gmt":"2008-08-19T19:31:50","guid":{"rendered":"http:\/\/d45h139.public.uconn.edu\/sites\/news\/?p=8379"},"modified":"2008-08-19T19:31:50","modified_gmt":"2008-08-19T19:31:50","slug":"nano-scale-instrument-aids-in-transfer-of-genetic-material","status":"publish","type":"post","link":"https:\/\/today.uconn.edu\/2008\/08\/nano-scale-instrument-aids-in-transfer-of-genetic-material\/","title":{"rendered":"Nano-scale Instrument Aids in Transfer of Genetic Material"},"content":{"rendered":"

\"Dr. Nejat Olgac, professor of Mechanical Engineering and head of UConn’s Advanced Laboratory for Automation, Robotics & Manufacturing (ALARM), and his team are developing a microscopic device called the Ros-Drill\u00a9 that can transfer genetic material into cells with greater accuracy and effectiveness than ever before achieved. This novel microinjection method – made possible through nanotechnology – offers diverse medical applications, including uses in stem cell research, drug development, artificial insemination and in vitro fertilization. It guides a glass pipette of 5-10 microns in diameter into cells of 50-100 microns in diameter.<\/p>\n

The method holds strong promise for in vitro fertilization, which has relied upon the conventional piezo-assisted ICSI technique. In contrast with the ICSI technique, which requires small amounts of mercury to stabilize the pipette tip when piezoelectric force pulses are applied, the Ros-Drill uses microprocessor-controlled rotational oscillations on a spiked micropipette (with 1-10 micron diameter) without mercury or piezo. Preliminary experimental trials indicate this technique gives high survival and fertilization rates as well as blastocyst formation rates.<\/p>\n

Dr. Olgac is partnering with researchers at Harvard University and the University of California Davis, as well as the Animal Science Department at UConn, to conduct biological testing. A patent is currently pending on the technique.<\/p>\n","protected":false},"excerpt":{"rendered":"

Dr. Nejat Olgac, professor of Mechanical Engineering and head of UConn’s Advanced Laboratory for Automation, Robotics & Manufacturing (ALARM), and his team are developing a microscopic device called the Ros-Drill\u00a9 that can transfer genetic material into cells with greater accuracy and effectiveness than ever before achieved. This novel microinjection method – made possible through nanotechnology […]<\/p>\n","protected":false},"author":122,"featured_media":8380,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_crdt_document":"","wds_primary_category":0,"wds_primary_series":0,"wds_primary_attribution":0,"footnotes":""},"categories":[1866],"tags":[],"magazine-issues":[],"coauthors":[],"class_list":["post-203443","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-engr"],"pp_statuses_selecting_workflow":false,"pp_workflow_action":"current","pp_status_selection":"publish","acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-04-21 09:05:45","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/203443","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/users\/122"}],"replies":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/comments?post=203443"}],"version-history":[{"count":0,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/203443\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media\/8380"}],"wp:attachment":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media?parent=203443"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/categories?post=203443"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/tags?post=203443"},{"taxonomy":"magazine-issue","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/magazine-issues?post=203443"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/coauthors?post=203443"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}