{"id":203939,"date":"2020-04-15T14:01:25","date_gmt":"2020-04-15T14:01:25","guid":{"rendered":"http:\/\/d45h139.public.uconn.edu\/sites\/news\/?p=29760"},"modified":"2024-08-10T21:06:26","modified_gmt":"2024-08-11T01:06:26","slug":"amidst-covid-19-outbreak-uconn-researchers-working-on-simple-low-cost-crispr-based-diagnostic-test-for-infectious-diseases","status":"publish","type":"post","link":"https:\/\/today.uconn.edu\/2020\/04\/amidst-covid-19-outbreak-uconn-researchers-working-on-simple-low-cost-crispr-based-diagnostic-test-for-infectious-diseases\/","title":{"rendered":"Amidst COVID-19 Outbreak, UConn Researchers Working on Simple, Low-Cost CRISPR-based Diagnostic Test for Infectious Diseases"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p><strong>By: Courtney Chandler, UConn School of Dental Medicine<\/strong><\/p>\n<p>Researchers in the Department of Biomedical Engineering\u2014 a shared department in the schools of Dental Medicine, Medicine, and Engineering\u2014have been working to develop a new, low-cost, CRISPR-based diagnostic platform to detect infectious diseases, including the novel coronavirus (SARS-CoV-2).<\/p>\n<p>With the recent outbreak of the SARS-CoV-2, the causative agent of COVID-19, Changchun Liu, associate professor, developed the \u201cAll-In-One-Dual CRISPR-Cas12a\u201d (AIOD-CRISPR) method to enable simple, rapid, ultrasensitive, visual detection of SARS-CoV-2 and HIV viruses, intended for use at home or in small clinics.<\/p>\n<p>Liu\u2019s lab has long focused on developing simple diagnostic technologies for infectious disease detection.<\/p>\n<p>\u201cThe recent outbreak of novel coronavirus has spread rapidly all over the world,\u201d Liu says. \u201cRapid and early detection of the\u00a0SARS-CoV-2\u00a0virus\u200b\u00a0will facilitate early intervention and reduce disease transmission risk. Our method has a great potential for developing next-generation point-of-care molecular diagnostics.\u201d<\/p>\n<p><a href=\"https:\/\/today.uconn.edu\/2020\/03\/amidst-covid-19-outbreak-uconn-researchers-working-simple-low-cost-crispr-based-diagnostic-test-infectious-diseases\/\">Click here to read more on UConn Today<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers in the Department of Biomedical Engineering\u2014 a shared department in the schools of Dental Medicine, Medicine, and Engineering\u2014have been working to develop a new, low-cost, CRISPR-based diagnostic platform to detect infectious diseases, including the novel coronavirus (SARS-CoV-2).<\/p>\n","protected":false},"author":122,"featured_media":216902,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"wds_primary_category":0,"wds_primary_series":0,"wds_primary_attribution":0,"footnotes":""},"categories":[1866],"tags":[],"magazine-issues":[],"coauthors":[2110],"class_list":["post-203939","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-engr"],"pp_statuses_selecting_workflow":false,"pp_workflow_action":"current","pp_status_selection":"publish","acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-07-04 05:01:06","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/203939","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/users\/122"}],"replies":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/comments?post=203939"}],"version-history":[{"count":1,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/203939\/revisions"}],"predecessor-version":[{"id":217087,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/203939\/revisions\/217087"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media\/216902"}],"wp:attachment":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media?parent=203939"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/categories?post=203939"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/tags?post=203939"},{"taxonomy":"magazine-issue","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/magazine-issues?post=203939"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/coauthors?post=203939"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}