{"id":211499,"date":"2024-04-02T07:15:21","date_gmt":"2024-04-02T11:15:21","guid":{"rendered":"https:\/\/today.uconn.edu\/?p=211499"},"modified":"2024-04-02T09:41:29","modified_gmt":"2024-04-02T13:41:29","slug":"want-to-contribute-to-scientific-research-theres-an-app-and-a-network-for-that","status":"publish","type":"post","link":"https:\/\/today.uconn.edu\/2024\/04\/want-to-contribute-to-scientific-research-theres-an-app-and-a-network-for-that\/","title":{"rendered":"Want to Contribute to Scientific Research? There\u2019s An App \u2013 and a Network \u2013 for That"},"content":{"rendered":"<p>In the exact same way that any average person opens their phone and taps on any ordinary app to check their email, or check the weather, or check social media, Kerry Gilmore swipes his thumb across his phone\u2019s glass screen and taps an app.<\/p>\n<p>This app isn\u2019t ordinary, though \u2013 it\u2019s a direct link to some of the sophisticated, automated <a href=\"https:\/\/gilmore.lab.uconn.edu\/\">instruments in his chemistry lab at UConn Storrs<\/a> as well as to information about and data produced through the lab\u2019s many research projects.<\/p>\n<p>But if they have the interest, any average person could tap that app, too.<\/p>\n<p>They can examine the data from experiments already run, automate processes to run experiments of their own, and contribute to those ongoing projects, all through the app.<\/p>\n<p>That easy access to active and developing science at UConn is completely by design.<\/p>\n<p>\u201cWhat we are trying to do is to open up access to being able to do research,\u201d says Gilmore, an assistant professor in the Department of Chemistry at UConn\u2019s College of Liberal Arts and Sciences.<\/p>\n<p>\u201cOne of the biggest limitations to being able to participate is not having access to the kinds of tools and technology that are necessary in order to do that science.\u201d<\/p>\n<p>A lot of chemistry training, he explains, involves learning and practicing how to conduct chemistry experiments, which can be limited both by location and the availability of equipment, as well as an individual\u2019s aptitude for learning those physical and technical skills.<\/p>\n<p>\u201cBut in theory, training should be about teaching you how to think, be creative and problem solve, and to come up with wonderful new solutions for things,\u201d Gilmore says.<\/p>\n<p>And it\u2019s that limiting dynamic that Gilmore and his team hope to change \u2013 one chemistry lab and one automated tool at a time \u2013 through this app, and through a unique and growing outreach program aimed at engaging Connecticut high school students who are interested in science.<\/p>\n<p><strong>Changing the Game<\/strong><\/p>\n<p>Gilmore is an organic chemist and a flow chemist. He came to UConn in 2020 after completing his post-doctoral fellowship and then working as a research group leader for six years at the <a href=\"https:\/\/www.mpikg.mpg.de\/en\">Max Planck Institute of Colloids and Interfaces<\/a> in Germany.<\/p>\n<p>Flow chemistry differs from traditional, or batch, chemistry in that the process involves reactants continuously traveling through tubing using pumping systems. The advantage of flow chemistry, explains Gilmore, is control.<\/p>\n<p>\u201cWe now have a stable set of conditions that we pass our solutions through,\u201d he says, compared to batch processes. \u201cTraditionally, we do chemistry a lot like cooking. You basically throw a bunch of stuff in a pot, heat it up, and hope it works. Flow chemistry is more like an assembly line, getting the same product every time.\u201d<\/p>\n<p>Conducting experiments using flow chemistry systems has typically meant that chemists needed not only access to the equipment but also the knowledge and skill to operate it. Chemistry has the potential to be dangerous \u2013 some reactants are caustic or flammable. Gases can be toxic. Things can blow up, both literally and figuratively.<\/p>\n<p>But in chemistry, as with so many fields, technological advancements are changing the game.<\/p>\n<p>\u201cThere&#8217;s lots of technology has been developed over the last 10, 15 years or so looking at automation, cloud computing, and everything that we can do online,\u201d Gilmore says, \u201cwhere we basically outsource everything from a technology standpoint, and we then have this interface that allows more of us to actually do things. We&#8217;ve taken the same approach, using automation and advanced instrumentation to remove the skills and expertise required, allowing more of us to do chemistry. We can simply tell it what we want to do, hit go, and the system does the rest.<\/p>\n<p>\u201cAnd what we realized is that if we can control that from a computer, that means we can control it from anywhere.\u201d<\/p>\n<figure id=\"attachment_211428\" aria-describedby=\"caption-attachment-211428\" style=\"width: 820px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-211428 img-responsive lazyload\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/monitor-crop-240320b0078-300x200.jpg\" alt=\"Standing Assistant Professor Kerry Gilmore and Edrik Morales-Rosa pose for the camera to demonstrate the Remote Research Network (RRN\" width=\"820\" height=\"546\" data-srcset=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/monitor-crop-240320b0078-300x200.jpg 300w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/monitor-crop-240320b0078-1024x683.jpg 1024w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/monitor-crop-240320b0078-1536x1025.jpg 1536w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/monitor-crop-240320b0078-2048x1367.jpg 2048w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/monitor-crop-240320b0078-630x420.jpg 630w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/monitor-crop-240320b0078-150x100.jpg 150w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/monitor-crop-240320b0078-996x665.jpg 996w\" data-sizes=\"(max-width: 820px) 100vw, 820px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 820px; --smush-placeholder-aspect-ratio: 820\/546;\" \/><figcaption id=\"caption-attachment-211428\" class=\"wp-caption-text\">Standing Assistant Professor Kerry Gilmore and Edrik Morales-Rosa pose for the camera to demonstrate the Remote Research Network (RRN)on March 20, 2024. (Sean Flynn\/UConn Photo)<\/figcaption><\/figure>\n<p>When Gilmore says \u201canywhere,\u201d that\u2019s exactly what he means \u2013 anywhere could be his office on the other side of the Chemistry building, or in the dorms across campus, in another part of the state, or in another part of the world.<\/p>\n<p>\u201cYou can be someone in Stamford doing this, but you can then also be someone in Bogota, Colombia, running these things,\u201d he says. \u201cAnd it&#8217;s the same experience, and it&#8217;s the same data.\u201d<\/p>\n<p>The system that Gilmore and his team built is called the <a href=\"https:\/\/remoteresearchnetwork.com\/\">Remote Research Network<\/a>, or RRN. <a href=\"https:\/\/apps.apple.com\/us\/app\/remote-research-network\/id6462894665\">The app is free to download<\/a>, and it\u2019s currently free to sign up, though they may begin charging nominal fees to cover the small cost of reactants used in the automated machines down the line as the network grows.<\/p>\n<p>Participants who join the network can view all of its active research projects. They can schedule and run experiments of their own. They can converse with other researchers and add their own creative thoughts and ideas to a project.<\/p>\n<p>All of the data generated through the experiments is considered open source and is stored on the network \u2013 everyone can see what worked and, just as important to Gilmore, what didn\u2019t.<\/p>\n<p>\u201cEverything that you run is open and live, and that, I think, is where we&#8217;re going to see the most transformational change in how we do science,\u201d he says. \u201cIf you&#8217;re looking at trying to bring in all of the beautiful data sciences that are being developed, and how we can continue to accelerate and figure out how we can solve more and more complicated problems, it doesn&#8217;t work if it&#8217;s just, \u2018Everything is great!\u2019 We need to know the full story \u2013 and that\u2019s something that\u2019s lacking in the way we share scientific data currently.\u201d<\/p>\n<p>Also important is that absolutely anyone can participate. No Ph.D. necessary. No background in chemistry involved. A college degree or high school diploma isn\u2019t required, either.<\/p>\n<p>Curiosity and interest are the only requisites.<\/p>\n<p><strong>Building Self Efficacy<\/strong><\/p>\n<p>For UConn students, access to instruments through the RRN means that they can work on research projects remotely at any hour of the day \u2013 not just when someone who knows how to operate the equipment is around.<\/p>\n<p>For other faculty at UConn, the RRN has the opportunity to break down barriers that might otherwise hinder research.<\/p>\n<p>\u201cOftentimes, the reason that we collaborate is because, if I&#8217;m an organic chemist studying how to deliver RNA or something like this, and I don\u2019t know how to make something, I have to go knocking on people\u2019s doors saying, \u2018Hey, will someone make this for me?\u2019\u201d Gilmore explains. \u201cThen, I have to convince that person that this is interesting enough, and hope they stay motivated enough in order to make the things I need to do my science. That&#8217;s often where things just fall apart.<\/p>\n<p>\u201cWhereas, what you could be able to do is say, \u2018I want to make this thing.\u2019 OK. I know I can use this automated platform, and it will remove all of the physical skills that are necessary in order to do this. That allows more people to participate and do the science they want to with fewer bottlenecks.&#8221;<\/p>\n<p>It also allows complete outsiders to enter the process \u2013 including high school students.<\/p>\n<p>\u201cThe overall idea for this is that if we can get more people involved, if more people can actually participate in research, then the higher the chances are that people can find that they are interested in this,\u201d says Gilmore. \u201cThey can build self-efficacy belief that \u2018I am a scientist. I can do this.\u2019\u201d<\/p>\n<p>A few years ago, Gilmore brought the RRN to <a href=\"https:\/\/ece.uconn.edu\/\">UConn\u2019s Early College Experience<\/a> program, or ECE. The ECE is a concurrent enrollment program that allows motivated high school students to take UConn courses at their high schools for both high school and college credit.<\/p>\n<p>Gilmore presented one particular piece of his research program to the ECE \u2013 a project involving an anti-malarial medication derived from a natural product called artemisinin that is synthesized from a plant called <em>Artemisia annua<\/em>, or sweet wormwood \u2013 and working with ECE members from local high schools, created a multi-stage outreach program where high school students could participate in research.<\/p>\n<p>Through the program, teams of students first grow their own plants, and then learn a process to extract compounds from the plants. They\u2019re provided with basic equipment to make their extracts, and smaller, automated equipment to test these compounds themselves. The data they generate is shared with their peers, and the compounds they find are working get delivered to Gilmore\u2019s lab.<\/p>\n<figure id=\"attachment_211440\" aria-describedby=\"caption-attachment-211440\" style=\"width: 820px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-211440 img-responsive lazyload\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/gilmore-9061-300x200.jpg\" alt=\"An app view of the the Remote Research Network\" width=\"820\" height=\"547\" data-srcset=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/gilmore-9061-300x200.jpg 300w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/gilmore-9061-1024x683.jpg 1024w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/gilmore-9061-768x512.jpg 768w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/gilmore-9061-1536x1024.jpg 1536w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/gilmore-9061-2048x1365.jpg 2048w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/gilmore-9061-630x420.jpg 630w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/gilmore-9061-150x100.jpg 150w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2024\/03\/gilmore-9061-998x665.jpg 998w\" data-sizes=\"(max-width: 820px) 100vw, 820px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 820px; --smush-placeholder-aspect-ratio: 820\/547;\" \/><figcaption id=\"caption-attachment-211440\" class=\"wp-caption-text\">An app view of the Remote Research Network. (Sean Flynn\/UConn Photo)<\/figcaption><\/figure>\n<p>Once their samples are loaded into the larger platforms at UConn, the students can then control the automated processes through the RRN app to run their own experiments and receive and analyze their own data.<\/p>\n<p>The outreach program was first piloted at Berlin High School, in Berlin, Connecticut; then extended to Platt High School in Meriden; and is now also at Norwich Free Academy in Norwich.<\/p>\n<p>And what started with sweet wormwood has expanded to any plants that the students want to try to cultivate and investigate \u2013 giving them an opportunity to expand their own unique and creative interests.<\/p>\n<p>\u201cWhat&#8217;s been really fascinating is you start to see them get excited and interested in this for multiple reasons,\u201d says Gilmore. \u201cThere are the kids that are really into the botany side of things. Awesome. They find that they get to take ownership over this portion of things. Then there are people that are interested in more of the engineering side of things, building the setups. Some are running the chemistry. And so, people can find their niches, discover their passions. If we have enough different areas that we can cover, we can get more people excited about this.\u201d<\/p>\n<p><strong>Building Community<\/strong><\/p>\n<p>It was through Platt High School\u2019s program that Edrik Morales \u201927 (CLAS) first met Gilmore and learned about his lab.<\/p>\n<p>\u201cI love science, specifically, the physical sciences \u2013 biology and chemistry, anything in that,\u201d says Morales, who graduated from Platt as valedictorian of his class in 2023 and started his first year at UConn Storrs this past fall, where he\u2019s double majoring in molecular and cell biology and chemistry.<\/p>\n<p>In his senior year of high school, Morales joined the RRN outreach program, visited Berlin High School, learned how to use the pumping systems, and contributed to the anti-malaria research program. But he joined the program late in his high school career, and when he came to UConn, he felt like his work with it wasn\u2019t done, yet.<\/p>\n<p>\u201cI&#8217;m not the type of person to leave things unfinished,\u201d Morales says. \u201cI like to involve myself in any way I can. I&#8217;m a really big fan of getting things done.<\/p>\n<p>He reached out to Gilmore, who invited him to join the lab. For the last few months, he\u2019s been working again on the RRN outreach program, but this time from the other side \u2013 helping to build and calibrate the pump systems that are distributed to the partner high schools.<\/p>\n<blockquote>\n  <p>Making these pumps \u2013 this is just kind of the tip of the iceberg, I feel, for what the future of education can look like in the sciences.\u201d  <cite> &#8212 Edrik Morales \u201927 (CLAS)<\/cite><\/p>\n<\/blockquote>\n<p>\u201cMaking these pumps \u2013 this is just kind of the tip of the iceberg, I feel, for what the future of education can look like in the sciences,\u201d he says. \u201cIt\u2019s giving students a grasp of what things may look like, if they want to work in a lab or do any form of research, and it helps establish that independence in them.\u201d<\/p>\n<p>Morales hopes to eventually go to medical school \u2013 his dream is to become a heart surgeon.<\/p>\n<p>And the systems he\u2019s helping to build now will assist in bringing an additional four high schools into the RRN outreach program in the near future, and hopefully more beyond that as the community around the program continues to grow.<\/p>\n<p>\u201cWhat we really want to do once we have a good handle on how to do this is to bring this to all of these other schools that don\u2019t have the same resources, that are in economically disadvantaged areas, that have much higher minority populations,\u201d Gilmore says, \u201cto try to use this as a way to encourage students who may not see themselves as scientists, who may not be thinking that they can go on and do these sorts of things, to give them that experience and that confidence so that they can try to pursue this, if that&#8217;s something they&#8217;re interested in.\u201d<\/p>\n<p>While the RRN is currently localized only to Gilmore\u2019s lab, his team\u2019s hope is to eventually add other labs, with other automated instruments, working on other types of research, in other places around the country and the world, into a vast network that can not only be inclusive, but also can help to accelerate the progression of science.<\/p>\n<p>And Gilmore himself hopes that, in the future, he won\u2019t have just two or three co-authors on a paper, but 50 or more \u2013 and that some of them will be the high school students who have participated in the outreach program and contributed data to his own projects.<\/p>\n<p>\u201cThere&#8217;s so many ways that we can participate, and what we&#8217;re trying to do with is facilitate community,\u201d says Gilmore. \u201cYou don&#8217;t have to have a specific program. If you&#8217;re the only one at your school who thinks that they can become a chemist, or an engineer, or a biologist, or anything else, great! Come on over. We can help you. You&#8217;re not alone. There is support for you. There are ways that you can advance in these things.<\/p>\n<p>\u201cBecause your choices shouldn&#8217;t be restricted to what you have access to if we can all access the same things.\u201d<\/p>\n<p>&nbsp;<\/p>\n<p><em>For more information about outreach opportunities at UConn, visit <\/em><a href=\"https:\/\/outreach.engagement.uconn.edu\/\"><em>outreach.engagement.uconn.edu<\/em><\/a><em>.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8216;What we are trying to do is to open up access to being able to do research&#8217; <\/p>\n","protected":false},"author":134,"featured_media":211429,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_crdt_document":"","wds_primary_category":0,"wds_primary_series":0,"wds_primary_attribution":0,"footnotes":""},"categories":[2226,2404,2460,2256,99,2235,2225,2227,2458],"tags":[],"magazine-issues":[],"coauthors":[2168],"class_list":["post-211499","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-clas","category-data-science","category-faculty","category-innovation","category-student-life","category-today-homepage","category-uconn-storrs","category-uconn-edu-homepage","category-undergraduates"],"pp_statuses_selecting_workflow":false,"pp_workflow_action":"current","pp_status_selection":"publish","acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-11 06:24:00","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/211499","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/users\/134"}],"replies":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/comments?post=211499"}],"version-history":[{"count":9,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/211499\/revisions"}],"predecessor-version":[{"id":211940,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/211499\/revisions\/211940"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media\/211429"}],"wp:attachment":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media?parent=211499"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/categories?post=211499"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/tags?post=211499"},{"taxonomy":"magazine-issue","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/magazine-issues?post=211499"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/coauthors?post=211499"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}