{"id":39049,"date":"2011-02-23T09:05:31","date_gmt":"2011-02-23T13:05:31","guid":{"rendered":"https:\/\/today.uconn.edu\/?p=39049"},"modified":"2011-07-29T15:12:39","modified_gmt":"2011-07-29T19:12:39","slug":"researchers-closing-in-on-link-between-genetics-alcoholism","status":"publish","type":"post","link":"https:\/\/today.uconn.edu\/2011\/02\/researchers-closing-in-on-link-between-genetics-alcoholism\/","title":{"rendered":"Researchers Closing in on Link Between Genetics, Alcoholism"},"content":{"rendered":"<figure id=\"attachment_39153\" aria-describedby=\"caption-attachment-39153\" style=\"width: 205px\" class=\"wp-caption alignright\"><a href=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2011\/02\/covault.jpg\"><img decoding=\"async\" class=\"size-medium wp-image-39153 img-responsive lazyload\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2011\/02\/covault-205x300.jpg\" alt=\"Jonathan M. Covault, M.D., Ph.D.\" width=\"205\" height=\"300\" data-srcset=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2011\/02\/covault-205x300.jpg 205w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2011\/02\/covault-287x420.jpg 287w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2011\/02\/covault-68x100.jpg 68w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2011\/02\/covault.jpg 342w\" data-sizes=\"(max-width: 205px) 100vw, 205px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 205px; --smush-placeholder-aspect-ratio: 205\/300;\" \/><\/a><figcaption id=\"caption-attachment-39153\" class=\"wp-caption-text\">Dr. Jonathan Covault is lead author of an article to be published in the journal <em>Alcoholism: Clinical &amp; Experimental Research<\/em> on the link between neuroactive steroids and alcohol dependence. (Janine Gelineau\/UConn Health Center)<\/figcaption><\/figure>\n<p>One of the risk factors for alcohol dependence may be genetic variations in certain enzymes that impact the production of neuroactive steroids, according to UConn Health Center researchers.<\/p>\n<p>Dr. Jonathan Covault, associate professor and director of Adult Psychiatry Residency Training Program in the UConn School of Medicine Department of Psychology, is the lead author of a study to be published in the May 2011 issue of Alcoholism: Clinical &amp; Experimental Research. The article is available through the journal\u2019s \u201cEarly View\u201d at <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1530-0277.2010.01425.x\/abstract\" target=\"_blank\">http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1530-0277.2010.01425.x\/abstract<\/a>.<\/p>\n<p>\u201cResults indicate that naturally occurring common genetic variations in two key enzymes required for the production of neuroactive steroids may influence the risk of developing alcohol dependence,\u201d Covault says. \u201cThis finding is among the first evidence that some behavioral effects of alcohol are related to the production of neuroactive steroids.\u201d<\/p>\n<p>Co-authors include Verica Milivojevic, a neuroscience graduate student in Covault\u2019s lab, Linda Burian, lab manager, Dr. Henry Kranzler, who recently left the UConn School of Medicine for the University of Pennsylvania, and Dr. Joel Gelernter of the Yale University School of Medicine.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>One of the risk factors for alcohol dependence may be genetic variations in certain enzymes that impact the production of neuroactive steroids, according to UConn Health Center researchers. Dr. Jonathan Covault, associate professor and director of Adult Psychiatry Residency Training Program in the UConn School of Medicine Department of Psychology, is the lead author of [&hellip;]<\/p>\n","protected":false},"author":111,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_crdt_document":"","wds_primary_category":0,"wds_primary_series":0,"wds_primary_attribution":0,"footnotes":""},"categories":[179,1],"tags":[],"magazine-issues":[],"coauthors":[57,2010],"class_list":["post-39049","post","type-post","status-publish","format-standard","hentry","category-uconn-health","category-uncategorized"],"pp_statuses_selecting_workflow":false,"pp_workflow_action":"current","pp_status_selection":"publish","acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-31 19:26:14","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/39049","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/users\/111"}],"replies":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/comments?post=39049"}],"version-history":[{"count":5,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/39049\/revisions"}],"predecessor-version":[{"id":40993,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/39049\/revisions\/40993"}],"wp:attachment":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media?parent=39049"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/categories?post=39049"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/tags?post=39049"},{"taxonomy":"magazine-issue","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/magazine-issues?post=39049"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/coauthors?post=39049"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}