{"id":85199,"date":"2013-10-28T09:50:21","date_gmt":"2013-10-28T13:50:21","guid":{"rendered":"https:\/\/today.uconn.edu\/?p=85199"},"modified":"2013-11-01T09:05:56","modified_gmt":"2013-11-01T13:05:56","slug":"the-international-language-of-science","status":"publish","type":"post","link":"https:\/\/today.uconn.edu\/2013\/10\/the-international-language-of-science\/","title":{"rendered":"The International Language of Science"},"content":{"rendered":"<figure id=\"attachment_84712\" aria-describedby=\"caption-attachment-84712\" style=\"width: 300px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_IQS.jpg\"><img decoding=\"async\" class=\"size-medium wp-image-84712   img-responsive lazyload\" alt=\"The Instituto Quimico De Sarria - Chemistry Institute of Sarria - in Catalunya, Spain.\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_IQS-300x200.jpg\" width=\"300\" height=\"200\" data-srcset=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_IQS-300x200.jpg 300w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_IQS-150x100.jpg 150w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_IQS.jpg 630w\" data-sizes=\"(max-width: 300px) 100vw, 300px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/200;\" \/><\/a><figcaption id=\"caption-attachment-84712\" class=\"wp-caption-text\">The Instituto Quimico De Sarria &#8211; Chemistry Institute of Sarria &#8211; in Catalunya, Spain.<\/figcaption><\/figure>\n<p>I can\u2019t say it plainly enough. My experience as a Fulbright fellow in Barcelona this past year transformed me, both professionally and personally. I returned to Connecticut not only with a broader perspective on my research but with a profound sense of place and the amazing impact of personal relationships.<\/p>\n<p>Perhaps most importantly, I returned with a sense of what I had always known but had never experienced quite like this: science is an international language, spoken around the world by people with a thirst for new knowledge.<\/p>\n<p>When I first arrived in Barcelona, my life was a maelstrom of impressions and emotions: new sights, new smells, late lunch and later dinner, hearing and speaking the Catalan language, the kindness of the locals, and somehow within it all, a sense of solitude. I had chosen to work at the Chemistry Institute of Sarria (<a href=\"http:\/\/www.iqs.edu\/en\/\">IQS<\/a>) with Professor <a href=\"http:\/\/www.iqs.edu\/en\/profile\/dr-antoni-planas:202-155\">Antoni Planas<\/a>, known to everyone as Toni. My host and his laboratory were the one constant during my transition.<\/p>\n<blockquote><p>Science is an international language, spoken around the world by people with a thirst for new knowledge.<\/p><\/blockquote>\n<p>Within a couple of weeks, I had learned the basics of day-to-day living, and I began to feel like l was a local. Science is inherently international, so the lab was a logical place to connect with something that was familiar to me.<\/p>\n<p><b>Getting proteins to work for us<\/b><\/p>\n<figure id=\"attachment_84716\" aria-describedby=\"caption-attachment-84716\" style=\"width: 300px\" class=\"wp-caption alignright\"><a href=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_sitges_group.jpg\"><img decoding=\"async\" class=\"size-medium wp-image-84716  img-responsive lazyload\" alt=\"With a group of friends in Sitges, Spain.\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_sitges_group-300x200.jpg\" width=\"300\" height=\"200\" data-srcset=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_sitges_group-300x200.jpg 300w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_sitges_group-150x100.jpg 150w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_sitges_group.jpg 630w\" data-sizes=\"(max-width: 300px) 100vw, 300px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/200;\" \/><\/a><figcaption id=\"caption-attachment-84716\" class=\"wp-caption-text\">With a group of friends in Sitges, Spain.<\/figcaption><\/figure>\n<p>Toni is world-famous for developing glycosynthases, which are engineered proteins that have their origins in sugar metabolism. The term glycosynthase was coined to indicate that the enzymes could use sugars (\u201cglyco\u201d) to synthesize (\u201csynthase\u201d) new polymers.<\/p>\n<p>Glycosynthases caught my eye because my research group at UConn synthesizes artificial sugars and characterizes how proteins bind to them. Our expanded sugars compete with natural sugars for protein binding sites and could have implications for preventing bacterial infections, among other applications. We wanted to know whether glycosynthases could utilize our expanded sugars in their reactions.<\/p>\n<figure id=\"attachment_84770\" aria-describedby=\"caption-attachment-84770\" style=\"width: 300px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_hugo_lab1.jpg\"><img decoding=\"async\" class=\"size-medium wp-image-84770   img-responsive lazyload\" alt=\"In the lab with Hugo Aragunde-Pazos, a graduate student at IQS.\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_hugo_lab1-300x200.jpg\" width=\"300\" height=\"200\" data-srcset=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_hugo_lab1-300x200.jpg 300w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_hugo_lab1-150x100.jpg 150w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_hugo_lab1.jpg 630w\" data-sizes=\"(max-width: 300px) 100vw, 300px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/200;\" \/><\/a><figcaption id=\"caption-attachment-84770\" class=\"wp-caption-text\">In the lab with Hugo Aragunde-Pazos, a graduate student at IQS.<\/figcaption><\/figure>\n<p>With help from Hugo Aragunde-Pazos, a graduate student at IQS, I prepared the enzymes and looked at their activity using compounds from my lab. Aside from doing the science itself, working in the laboratory with Spanish students was a curriculum in language, both Spanish and Catalan. Although I\u2019ve been exposed to the Spanish language \u2013 my wife is Colombian and Spanish \u2013 I spent significant energy on simple communication. My labmates were remarkably helpful and patient with my slow language skills.<\/p>\n<p>Eventually, the language barrier broke down, and I was able to easily communicate, but the experience made a strong impression on me. Now I better empathize with the challenges that face international researchers in the U.S.<\/p>\n<p>The results of the research showed that our sugars are weak substrates for glycosynthases; this is actually encouraging because our sugars shouldn\u2019t be degraded by natural enzymes if they are used as drugs. It also allows us to develop new enzymes, via mutation and screening, that will <i>only<\/i> accept our sugars.<\/p>\n<p><b>The heart of the science<\/b><\/p>\n<p>In the spirit of the Fulbright program, which encourages open exchanges of ideas with people from different parts of the world, I interviewed a few scientists in Barcelona whose research interests are similar to mine. I spoke with my friend, <a href=\"http:\/\/sciencegeist.net\/interview-with-xavier-salvatella-by-mark-peczuh\/\">Xavi Salvatella<\/a>; Ernest Giralt, who was a collaborator with my Ph.D. advisor; and Lluis Ribas, a scientist and entrepreneur working on the development of new antibiotics. All are researchers at Barcelona\u2019s <a href=\"http:\/\/www.irbbarcelona.org\/index.php\/en\/research\/programmes\/chemistry-and-molecular-pharmacology\/molecular-biophysics\/people\/xavier-salvatella\">Institute for Research in Biomedicine<\/a>.<\/p>\n<p>In the interviews, I asked about their research programs, how they ended up at the IRB, and what it meant for them to be doing research in Barcelona. Each of them expressed a strong connection to Catalunya \u2013 their region of Spain, and to their families and friends who live there.<\/p>\n<figure id=\"attachment_84709\" aria-describedby=\"caption-attachment-84709\" style=\"width: 223px\" class=\"wp-caption alignright\"><a href=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_gigante.jpg\"><img decoding=\"async\" class=\"size-medium wp-image-84709  img-responsive lazyload\" alt=\"P10-foot-tall puppets dance through the streets on a carpet of flowers in Sitges, Spain.\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_gigante-223x300.jpg\" width=\"223\" height=\"300\" data-srcset=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_gigante-223x300.jpg 223w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_gigante-313x420.jpg 313w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_gigante-74x100.jpg 74w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_gigante-280x375.jpg 280w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_gigante.jpg 373w\" data-sizes=\"(max-width: 223px) 100vw, 223px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 223px; --smush-placeholder-aspect-ratio: 223\/300;\" \/><\/a><figcaption id=\"caption-attachment-84709\" class=\"wp-caption-text\">10-foot-tall puppets dance through the streets on a carpet of flowers in Sitges, Spain.<\/figcaption><\/figure>\n<p>It struck me that these things \u2013 identification with \u201chome\u201d and close personal relationships \u2013 make any group unique, but it is also common to <i>all<\/i> groups. I realized that these scientists have made choices that balance their scientific passion with their cultural identification and feelings about what is \u201chome.\u201d The realization has kindled a desire in me to remember the importance of people and place in my daily life.<\/p>\n<p>You simply can\u2019t go to Catalunya without taking a few excursions to take in cultural sights. A highlight was a day trip to the nearby beach town of Sitges on Corpus Christi, a holiday, to see the \u201ccarpets of flowers,\u201d kind of like a stationary Rose Parade.<\/p>\n<p>A series of 10-foot-tall puppets, known as \u201cgigantes,\u201d danced through the streets while simultaneously destroying the carpets. My companions couldn\u2019t explain why the gigantes had to destroy the flower creations, but it seemed symbolic to me.<\/p>\n<p>It\u2019s also difficult to talk about Spain without mentioning food. Paella was both the food and the entertainment at a party in honor of Toni, who had just received the <a href=\"https:\/\/picasaweb.google.com\/101207502592673960480\/OpeningCeremony#5906293183103217970\">Fischer Prize<\/a> at the 2013 European Carbohydrate Symposium. After we had consumed mountains of paella, there was a viewing of a video, \u201cPlanas Style,\u201d a Catalan rendition of Psy\u2019s \u201cGangnam Style.\u201d It was filmed in honor of Toni, but also to parody him. I suppose this is evidence that some cultural phenomena, especially pop culture, are truly international.<\/p>\n<figure id=\"attachment_84713\" aria-describedby=\"caption-attachment-84713\" style=\"width: 225px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_paella.jpg\"><img decoding=\"async\" class=\"size-medium wp-image-84713  img-responsive lazyload\" alt=\"Paella at a party in honor of host Toni Planas.\" data-src=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_paella-225x300.jpg\" width=\"225\" height=\"300\" data-srcset=\"https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_paella-225x300.jpg 225w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_paella-315x420.jpg 315w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_paella-75x100.jpg 75w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_paella-280x375.jpg 280w, https:\/\/today.uconn.edu\/wp-content\/uploads\/2013\/10\/Peczuh_paella.jpg 375w\" data-sizes=\"(max-width: 225px) 100vw, 225px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 225px; --smush-placeholder-aspect-ratio: 225\/300;\" \/><\/a><figcaption id=\"caption-attachment-84713\" class=\"wp-caption-text\">Paella at a party in honor of host Toni Planas.<\/figcaption><\/figure>\n<p>Now I\u2019ve returned to the Connecticut I know and love, but I often find myself reminiscing about the cultural immersion I experienced in a land so different from mine. Beyond the scientific collaboration that I sought on my trip, I now have a deeper understanding of how Catalans see the world and themselves. I am attached to both the specifics of this perspective \u2013 in terms of Catalunya\u2019s uniqueness within Spain \u2013 and also the broader sense of place and relationships.<\/p>\n<p>As I watch the autumn leaves change and fall to the ground and notice the red barns rising over Horsebarn Hill, I can only hope that I revealed a Nutmegger\u2019s perspective of the world to my new friends in Barcelona in the same way that they shared their culture with me.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A Fulbright Fellowship enabled chemistry professor Mark Peczuh to work with research colleagues in a lab in Spain.<\/p>\n","protected":false},"author":58,"featured_media":84712,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_crdt_document":"","wds_primary_category":0,"wds_primary_series":0,"wds_primary_attribution":0,"footnotes":""},"categories":[88,2076,1],"tags":[],"magazine-issues":[],"coauthors":[117],"class_list":["post-85199","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-global-affairs","category-research","category-uncategorized"],"pp_statuses_selecting_workflow":false,"pp_workflow_action":"current","pp_status_selection":"publish","acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-27 11:15:43","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/85199","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/users\/58"}],"replies":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/comments?post=85199"}],"version-history":[{"count":5,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/85199\/revisions"}],"predecessor-version":[{"id":85336,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/posts\/85199\/revisions\/85336"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media\/84712"}],"wp:attachment":[{"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/media?parent=85199"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/categories?post=85199"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/tags?post=85199"},{"taxonomy":"magazine-issue","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/magazine-issues?post=85199"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/today.uconn.edu\/wp-rest\/wp\/v2\/coauthors?post=85199"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}