Quarterly Recap of Pharmacy Faculty Research Grants – FY 2021 Q2

Recapping the quarter beginning October 1, 2020 through December 31, 2020, the UConn School of Pharmacy congratulates the following Departments of Pharmaceutical Sciences and Pharmacy Practice faculty and their teams for their FY 2021 Q2 research grant awards* totaling $942,819.00:

Close up look at a section of the UConn School of Pharmacy Building

Recapping the quarter beginning October 1, 2020 through December 31, 2020, the UConn School of Pharmacy congratulates the following Departments of Pharmaceutical Sciences and Pharmacy Practice faculty and their teams for their FY 2021 Q2 research grant awards* totaling $942,819.00:

Department of Pharmaceutical Sciences

Bodhisattwa Chaudhuri, Ph.D.
Takeda Pharmaceuticals
Applicability and calibration of CFD-DEM model for pharmaceutical processes.
12/02/2020 $130,012.

This study will include scale-up activities along with providing guidance to reduce the computational time bereft of compromising on the accuracy of the results. – Dr. Chaudhuri

Bodhisattwa Chaudhuri, Ph.D. (with Dr. W. K. Anson Ma, CBE )
Genentech
3D printing of drug laden tablets
12/01/2020 $150,000

The goal of study is to explore different 3D printing techniques for manufacturing tablets and fabricate tablets at desired drug loadings and investigate the properties of these dosage form. – Dr. Chaudhuri

Na Li, Ph.D.
Center for Pharmaceutical Processing Research
CPPR: Continuous and scalable manufacture of redispersible nanoparticles
11/19/2020 $90,000

The major goal of this project is to study the formation and spray drying stability of soft nanoparticles. We are identifying particle growth mechanisms in the solution and solid states and the impact of particle property, stabilizer choice, and processing conditions on particle stability. – Dr. Li

Xiuling Lu, Ph.D.
Bausch Health
In Vitro Drug Release Assessment for Semi-Solid Products
12/01/2020 $30,000

The goal of this project is to evaluate in vitro drug release from ophthalmic ointments. – Dr. Lu

Xiuling Lu, Ph.D. and Robin Bogner, Ph.D.
Janssen Pharmaceuticals
Cryopreservation of T cells with exploration of cell freeze drying
11/20/2020 $409,797

The goal of this project is to investigate the impact of cryopreservation and freeze-drying of Jurkat T cells on cell membrane integrity and viability. – Dr. Lu

 

Department of Pharmacy Practice

Nathaniel Rickles, Ph.D., BCPP
DHHS/SAMHSA/Substance Abuse and Mental Health Services Administration/CT Department of Mental Health and Addiction Services
Acamdemic Detailing on Opioid Safety in CT
10/20/2020 $128,000

This is a grant that supports 1:1 educational outreach visits, on opioid safety topics (prescription drug monitoring program, naloxone, medication-assisted treatments, and new modules to be developed) between trained Connecticut health district staff and pharmacists and prescribers in their health districts. The goal of the program to facilitate clinician behavior change toward clinical behaviors that support optimal safe use of opioids, reduce risk of overdose, and facilitate treatment for an opioid use disorder. – Dr. Rickles

Nathaniel Rickles, Ph.D., BCPP
Pfizer
Patient Adherence Manuscript and Literature Review
10/30/2020, $24,998

This award supports an extensive systematic review of validated self-reported medication adherence tools and report on characteristics of included tools that make them most useful for clinical practice and use. – Dr. Rickles

* Grant awards listed in UConn’s Office of the Vice President for Research OVPR’s Quarterly Reports are those reported as fully executed

SUPPORT  the Department  of Pharmaceutical Sciences