Recapping the quarter beginning July 1, 2021 through September 30, 2021, the UConn School of Pharmacy congratulates the following Departments of Pharmaceutical Sciences and Pharmacy Practice faculty and their teams for their FY 2022 Q1 research grant awards totaling $2,773,682:
Pharmaceutical Sciences:
Diane J. Burgess, Ph.D.
DHHS/FDA/Food and Drug Administration
Enhancement and Validation of In Vitro – In Vivo Correlation Method for Long Acting Injectable Drug Products to Accelerate Their Generic Development
09/24/2021 $1,310,263
Bodhisattwa Chaudhuri, Ph.D.
Sarepta Therapeutics
Molecular Modeling of Adeno-Associated VIrus (AAVs) Aggregation and Their Interaction with Hydrophobic Surface
09/01/2021 $60,022
Research Overview: “The overall objective of this proposal is to understand the molecular level aggregation behavior of viral capsids and their tendency to be absorbed on hydrophobic surfaces with the effect of surface charge and solution ionic strength/osmolality. Moreover, revealing the role of free DNA towards this aggregation process is also warranted. This experimentally validated model will serve as a predictive tool to improve purification and reduce deleterious effects on vector transduction efficiency, biodistribution, and immunogenicity following in vivo administration.” – Dr. Chaudhuri
Pharmacy Practice:
Stephanie Gernant, Pharm.D., M.S.
University of Texas, Tyler
A real-world retrospective comparison of the safety and efficacy of apixaban and rivaroxaban in obese and morbidly obese NVAF patients
09/27/2021 $4,099
Nathaniel Rickles, Pharm.D., Ph.D.
DHHS/FDA/Food and Drug Administration
Comparative Trial of Different Packaging Components of an Opioid Packaging Solution on Opioid Safety Outcomes
09/24/2021 $1,399,298
Research Overview “This FDA funded contract is to use mixed methods and multiple clinical sites to determine the feasibility and impact of pre-packaging opioids on the prescribing, dispensing, and patient utilization of opioids for multiple pain conditions.” – Dr. Rickles
