UConn Health

Bone-forming cells inside a living bone from a newborn mouse. The cells were engineered to contain a fluorescent green protein that senses cyclic GMP, a molecule that stimulates bone growth. In a recently published study in eLife, Leia Shuhaibar and others at UConn Health showed that these cells produce less cyclic GMP under conditions that resemble those in people with achondroplasia (dwarfism). Understanding how cyclic GMP production is regulated could contribute to improved therapies for achondroplasia.

Fertility Study Offers Unexpected Lead on Dwarfism

In the most common type of dwarfism, the fibroblast growth factor receptor is always 'on' so bones don’t grow enough. UConn Health researchers found a way to block that function in the lab.

An apple with a heart-shape carved out of it. (Getty Images)

Top 10 Heart Health Myths Busted

'I'm not very overweight, so I don't need to watch what I eat.' Experts from UConn Health’s Pat and Jim Calhoun Cardiology Center debunk this and other common myths about cardiovascular health.

Dr. Marc Lalande, founding chairman of the Department of Genetics and Genome Sciences. (Lanny Nagler for UConn Health).

Giving Silenced Genes a Voice

UConn Health researchers generated cells that expressed the maternal copy of the Prader-Willi gene that, when silenced, causes the life-threatening disorder.

This biodegradable piezoelectric pressure sensor developed by the Nguyen Research Group at UConn could be used by doctors to monitor chronic lung disease, brain swelling, and other medical conditions before dissolving safely in a patient’s body. (Image courtesy of Thanh Duc Nguyen)

Biodegradable Sensor Monitors Pressure in the Body then Disappears

The new sensor is designed to replace existing implantable pressure sensors that have potentially toxic components, which must be removed after use.

Computer illustration of cytotoxic T-lymphocytes attacking a cancer cell. (Juan Gaertner/Science Photo Library via Getty Images)

Removing the Immunotherapy Blindfold

UConn Health researchers are developing a technology that can identify which patients will respond to immunotherapy, with the goal of extending the benefits of the treatment to a wider group of patients.

UConn medical students gather around a digital 3-D simulation of a cadaver. (Sean Flynn/UConn Photo)

Training the Doctors of Tomorrow

From UConn Health Journal: The dean of the School of Medicine discusses the school's new curriculum, a year after it was introduced in fall 2016.

Five UConn Health researchers have won a new type of NIH grant designed to foster innovation and risk-taking in basic medical research. From left, Duygu Ucar, Justin Cotney, Brenton Graveley, Zhengqing Oyang, and Stefan Pinter, at the Cell and Genome Sciences Building in Farmington. (Peter Morenus/UConn Photo)

MIRA Awards Reflect Innovation of UConn Scientists

Five UConn Health researchers have won a new type of NIH grant designed to foster innovation and risk-taking in basic medical research.

It's been shown that the more physicians focus on exercise, the more likely it is that patients will exercise, writes UConn Health's Brad Biskup.

Why Walking with Your Doctor Could be Better Than Talking with Your Doctor

It's been shown that the more physicians focus on exercise, the more likely it is that patients will exercise, writes UConn Health's Brad Biskup.

Close up of women and DNA helixes. (Getty Images)

Number of Genetic Markers Linked to Lifespan Triples

A new study by UConn researchers and others increases the number of genetic variants linked to lifespan to 25. These markers offer potentially modifiable targets to reduce the risk of an early death and improve health.

A local artist is brightening the holiday season using his coloring books as art therapy for his fellow UConn Health patients living with sickle cell and other diseases. (Tina Encarnacion/UConn Health Photo)

Coloring Away the Pain

A local artist is brightening the holiday season using his coloring books as art therapy for his fellow UConn Health patients living with sickle cell and other diseases.