Research & Discovery

For every drug that scientists develop against bacteria (a "move"), bacteria respond with mutations that confer resistance to the drug. In this paper, we show that these "moves" by bacteria can be predicted in silico ahead of time by the Osprey protein design algorithm. We used Osprey to prospectively predict in silico mutations in Staphylococcus aureus against a novel preclinical antibiotic, and validated their predictions in vitro and in resistance selection experiments. Image created for this paper by Lei Chen and Yan Liang. (Courtesy of Duke University).

Getting Ahead of Antibiotic-resistant Bacteria

A UConn medicinal chemist has developed software with a colleague at Duke that could help make more resilient antibiotics.

Arash Zaghi, assistant professor of civil and environmental engineering, demonstrates a creativity experiment with several students at his office. (Peter Morenus/UConn Photo)

Engineering Education Study Looks to Tap Strengths of ADHD Students

UConn researchers are seeking to keep potential pioneers in the field of engineering.

Dorit Bar-On, outside Manchester Hall on Oct. 29, 2014. (Peter Morenus/UConn Photo)

Philosopher Focuses on Questions of Self-Knowledge, Truth

Dorit Bar-On is developing a 'humanities version' of a scientific lab, with collaborative research among a variety of scholars in the field of communication.

Brian Huey reviews microscope data at IMS on Jan. 16, 2015. (Peter Morenus/UConn Photo)

Building the Next Generation of Efficient Computers

A UConn researcher has uncovered important information about the kinetics behind a new form of computer memory.

An interactive digital wall in the lobby of Boston Children's Hospital was designed by researchers at the University of Connecticut.

Hospital’s High-tech Wall Opens Doors to Imagination

UConn faculty and students designed an interactive wall for the Boston Children's Hospital lobby.

Sailing the Mid-Century Arctic

Geographer Scott Stephenson is charting the possibilities for the future of Arctic shipping lanes under various climate change scenarios.

Psychology professor Crystal Park at her yoga studio in Mystic. (Sean Flynn/UConn Photo)

From Resolution to Ritual: Why People Start and Stick With Yoga

A new study notes that while many begin yoga for the health benefits, those who continue often say spirituality is the reason.

Amy Anderson, left, professor of pharmaceutical science and Dennis Wright, professor of pharmaceutical science on Jan. 8, 2014. (Peter Morenus/UConn Photo)

Advancing Knowledge: Research

A glimpse into this past year's discoveries by UConn researchers.

A view of the Thomas J. Meskill Law Library at the University of Connecticut School of Law in Hartford. (Peter Morenus/UConn Photo)

UConn Law Creates Two New Master’s Degrees

The new degree programs in human rights and social justice and energy and environmental law are intended to meet emerging needs in society.

Jill Wegrzyn, ecology and evolutionary biology assistant research professor, at a Christmas tree farm. (Sean Flynn/UConn Photo)

Big Data and the Science of the Christmas Tree

A UConn bioinformatics researcher is helping develop tools that will enable more scientists to start finding meaning in massive amounts of data.